Ebook Organic Synthesis: The Disconnection Approach, by Stuart Warren
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Organic Synthesis: The Disconnection Approach, by Stuart Warren
Ebook Organic Synthesis: The Disconnection Approach, by Stuart Warren
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A workbook providing additional examples, problems, and solutions for use with Warren's Organic Synthesis: The Disconnection Approach. Exercises correspond to chapters in the main text. Problems of special ease or difficulty are labeled for optional use. Workbook includes a formula index of all target molecules contained in the text and workbook.
- Sales Rank: #1859788 in Books
- Published on: 1991-01-15
- Original language: English
- Number of items: 1
- Dimensions: 9.02" h x .87" w x 6.04" l, .0 pounds
- Binding: Paperback
- 404 pages
Review
?The authors have succeeded admirably in the updating of a classic in the pedagogy of organic chemistry.? ( Journal of Medicinal Chemistry , August 2009)
?This book is suitable for advanced undergraduate students, researchers and professional chemists. Both the writing and the diagrams are simple and clear.? ( Reviews, May 2009)
From the Publisher
A workbook providing additional examples, problems, and solutions for use with Warren's Organic Synthesis: The Disconnection Approach. Exercises correspond to chapters in the main text. Problems of special ease or difficulty are labeled for optional use. Workbook includes a formula index of all target molecules contained in the text and workbook.
From the Back Cover
This book will help students to design their own organic synthesis, giving a wide coverage of synthetic methods. The disconnection approach is used throughout so that starting materials are chosen after analysing the structure of the target molecule. There are forty chapters: those on the synthesis of given types of molecule alternate with strategy chapters in which the methods just learnt are placed in a wider context. The instructional chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The number and position of these functional groups provides the classification for these chapters. The strategy chapters cover questions of selectivity, protection, and stereochemistry, and develop more advanced strategic thinking via reagents specially designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given, and further examples can be found in the accompanying workbook which also gives many problems and solutions classified in the same way as the main text. The book will also assist more experienced chemists who feel they are out of touch with present day thinking on the subject.
Workbook for Organic Synthesis: The Disconnection Approach The workbook which supports this text provides an extra selection of examples. Each example is analysed in the same way as those in the main text with disconnections followed by synthesis, allowing the student to explore a wider range of types of target molecule and synthetic method. The main function of the workbook is, however, to provide a graded series of problems which extend the student's experience of the types of molecules being synthesised by organic chemists. These, together with the examples, are classified into the same 40 chapters as the main text so that it is possible to use them in conjunction with it. Each problem is followed by a suggested solution or solutions analysed in the same way as the examples and no methodology other than that introduced in the main text is required. Examples and problems are interspersed to provide a developing chain of argument.
Most helpful customer reviews
1 of 1 people found the following review helpful.
I really like the approach of this book
By Arc
I bought this book as part of a required text for an advanced organic chemistry class as an undergraduate. I really like the approach of this book! It offers various strategies of "disconnecting" complex organic molecules into smaller and more recognizable molecules which is very helpful if you are interested in working in a synthetic chemistry lab or research. After taking two semesters of undergrad organic chemistry, I was able to understand and logically progress from the simple molecules that one can disconnect from larger molecules. It also offers various useful tables, and reactions from actual organic chemistry literature that demonstrate how a particular disconnection can lead to simple starting materials.
If you are buying this book to learn the "Disconnection Approach," I highly recommend that you also buy the companion book: "Workbook for ORGANIC SYNTHESIS The Disconnection Approach (2nd ed.)."
7 of 7 people found the following review helpful.
Excellent, definitive
By Chris Joslin
An amazing and incisive description of retrosynthetic techniques, written at the advanced undergraduate level.
My criticisms would be:
(1) Rather too terse at some points; a few more words would make it flow more smoothly;
(2) As the book progresses, there are increasing references to "Strategy and Control", and more annoyingly, the workbook; the text is not entirely self contained, and I should not have to purchase the workbook for simple clarification;
(3) The index is really poor. This is the book's principal failing, and makes hunting around for cross references much harder than it should be.
Nevertheless, this is a wonderful work on an exciting and important area of organic chemistry, and I heartily recommend it.
0 of 0 people found the following review helpful.
Really good with minor stupid mistakes
By Pen Name
I leArned quite a bit. It has some mistakes though. They kept calling the Robinson annulation "annelation".
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